4-(2,4-dimethoxy-3,6-dimethyl-benzoyl)oxy-2-hydroxy-3,6-dimethyl-benzoic acid
DIFFRACTIC ACID
CAS: 436-32-8
Molecular Formula: C20H22O7
4-(2,4-dimethoxy-3,6-dimethyl-benzoyl)oxy-2-hydroxy-3,6-dimethyl-benzoic acid - Names and Identifiers
4-(2,4-dimethoxy-3,6-dimethyl-benzoyl)oxy-2-hydroxy-3,6-dimethyl-benzoic acid - Physico-chemical Properties
| Molecular Formula | C20H22O7 |
| Molar Mass | 374.38 |
| Density | 1.260±0.06 g/cm3(Predicted) |
| Melting Point | 189～190℃ |
| Boling Point | 604.9±55.0 °C(Predicted) |
| Solubility | Soluble in methanol, ethanol, DMSO and other organic solvents |
| Appearance | Powder |
| pKa | 2.66±0.25(Predicted) |
| Storage Condition | 2-8℃ |
| MDL | MFCD01684770 |
| Physical and Chemical Properties | Powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Usnea Usnea diffracta Vain, Dihuang genus Dihuang Rehmannia glutinosa (Gaetn.) Libosch. ex Fisch. et Mey.. |
| In vivo study | Diffractaic acid shows an analgesic effect by Acetic acid-induced writhing and tail-pressure methods in mice. |
4-(2,4-dimethoxy-3,6-dimethyl-benzoyl)oxy-2-hydroxy-3,6-dimethyl-benzoic acid - Reference
| Reference Show more | 1. Ma Ying Hua Tian Ting Ting Jie Wei Wei et al. Simultaneous determination of three phenolic acids in pine nut by HPLC-ESI-MS/MS [J]. Chinese Journal of Traditional Chinese Medicine, 2015, 40(24):4884-4889. 2. Ma Yinghua, Tian Tingting, Jie Weiwei, et al. Identification of chemical constituents of main phenolic acids in pine nut by UHPLC-Triple-TOF-MS method [J]. Chinese Herbal Medicine, 2016, 47(003):392-400. 3. Jin, Yiran, et al. "UHPLC-Q-TOF-MS/MS-oriented characteristic components dataset and multivariate statistical techniques for the realistic quality control of Usnea." RSC advances 8.28 (2018): 15487-15500.https://DOI: 10.1039/C8RA00081F 4. [IF=3.361] Yiran Jin et al."UHPLC-Q-TOF-MS/MS-oriented characteristic components dataset and multivariate statistical techniques for the holistic quality control of Usnea."Rsc Adv. 2018 Apr;8(28):15487-15500 |
4-(2,4-dimethoxy-3,6-dimethyl-benzoyl)oxy-2-hydroxy-3,6-dimethyl-benzoic acid - Reference Information
| use | it is known that Usnea lichens contain difon and usnic acid. the extraction conditions of Usnea lichens, which can be applied to skin topical agents such as whitening agents and reduce the content of usnic acid, were studied. |
| biological activity | Diffractaic acid is the main component of U. longissimi and can be used as an effective proapoptotic agent in various disease studies. Diffractaic acid also has analgesic and antipyretics effects. |
| in vivo study | Diffractaic acid show an analgesic effect by Acetic acid-induced writhing and tail-pressure methods in mice. |
| chemical properties | powder, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Usnea Usnea diffracta Vain, Dihuang belongs to Dihuang Rehmannia glutinosa (Gaetn.) Libosch. ex Fisch. et Mey.. |
Last Update：2024-04-09 20:49:11
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